FIND CLINICAL TRIALS

 

IDO1 = INDOLEAMINE 2,3-DIOXYGENASE 1

 
 
 

Incyte is developing an IDO1 inhibitor.

IDO1 is an immunosuppressive enzyme that leads to regulatory T-cell generation and activation and allows tumors to escape from immune surveillance. Inhibition of immunomodulatory mechanisms with IDO1 inhibitor-based combination therapy may re-establish antitumor immunity.

MOLECULE LIBRARY

image show jak target.image of pi3kδ target.image of fgfr target.image of brd target.image of pim target molecule.image of lsd1 target molecule.image shows ido1 target.image shows arg target.image of pd-1 target molecule. image of gitr target molecule. image of ox40 target molecule.  image of Tim-3 target moleculeimage of Lag-3 target moleculeimage of Axr target molecule