FIND CLINICAL TRIALS

 

PD-1 = PROGRAMMED CELL DEATH-1

 
 
 

Incyte is developing a PD-1 antibody.

PD-1 is a protein expressed on multiple immune cells, including T cells, and acts as a key checkpoint in tumor-induced immune suppression.

Activation of PD-1 can reduce effector T-cell activity and facilitate regulatory T-cell formation, while down-regulating expression of anti-apoptotic molecules and pro-inflammatory cytokines. Blocking PD-1 can increase antitumor immunity through enhancing T-cell activity.

MOLECULE LIBRARY

image show jak target.image of pi3kδ target.image of fgfr target.image of brd target.image of pim target molecule.image of lsd1 target molecule.image shows ido1 target.image shows arg target.image of pd-1 target molecule. image of gitr target molecule. image of ox40 target molecule.  image of Tim-3 target moleculeimage of Lag-3 target moleculeimage of Axr target molecule